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A novel method to enhance efficacy of topical drugs by condom occlusion in penile dermatoses
  1. Sanjeev Gupta1,
  2. Ravi Shankar Jangra1,
  3. Saurabh Swaroop Gupta1,
  4. Ajinkya Vinayak Gujrathi1,
  5. Sunita Gupta2
  1. 1 Department of Dermatology, Maharishi Markandeshwar Deemed to be University, Mullana Ambala, Haryana, India
  2. 2 Department of Medicine, Maharishi Markandeshwar Deemed to be University, Mullana Ambala, Haryana, India
  1. Correspondence to Dr Sanjeev Gupta, Dermatology, Maharishi Markandeshwar University, Haryana 133207, India; sanjeevguptadr{at}gmail.com

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Topical application and stay-on time of topical drugs have always been an issue in cases of penile dermatoses, as the applied drug gets wiped away almost immediately by the undersurface of preputial skin or by the undergarments leading to therapeutic failure. We propose a simple solution to this problem by asking patient to wear a condom after application of the drug. Condoms have already been used for drug delivery in males and females, notably for the containment and focused delivery of spermicides, vasodilators such as niacin, sildenafil citrate and nitroglycerin and male desensitising agents such as benzocaine,1 but we could …

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Footnotes

  • Collaborators Gupta S, Jangra RS, Gupta SS, Gujrathi AV, Gupta S.

  • Contributors All authors have contributed extensively in designing, writing, research and approval of this manuscript. Dr SG contributed in designing, conducting study, writing paper and literature search. Dr RSJ: contributed in designing, conducting study, writing paper and literature search. Dr SSG: contributed in conducting study. writing paper and literature search. Dr AVG: contributed in conducting study. writing paper and literature search. Dr SG: contributed in designing, conducting study, writing paper and literature search.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Not required.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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