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Acupuncture versus sham acupuncture for simple obesity: a systematic review and meta-analysis
  1. Yu-Mei Zhong1,
  2. Xiao-Chao Luo1,
  3. Yang Chen1,
  4. De-Li Lai1,2,
  5. Wen-Ting Lu1,
  6. Ya-Nan Shang1,
  7. Lin-Lin Zhang1,
  8. Hai-Yan Zhou1
  1. 1 Acupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu, China
  2. 2 The Affiliated Hospital, School of Medicine, UESTC, Chengdu Women’s and Children’s Central Hospital, Chengdu, China
  1. Correspondence to Dr Hai-Yan Zhou, Acupuncture and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China; zhouhaiyan{at}


Obesity is a growing chronic health problem worldwide. Studies about acupuncture for obesity treatment are many. But there are some doubts about the effectiveness of acupuncture versus sham acupuncture in treating obesity due to its lack of medical evidence. Therefore, the aim of this study is to assess the efficacy of acupuncture for obesity treatment and provide clinic evidence. Four English databases (PubMed, EMBASE, Web of Science and Cochrane Central Register of Controlled Trials) and four Chinese databases (China National Knowledge Infrastructure, Chinese BioMedical Database, Chinese Scientific Journal Database and Wan-Fang Data) were searched from their receptions to August 2019. Randomized controlled trials (RCTs) using the comparison between acupuncture and sham acupuncture to treat simple obesity were included. The primary outcome of body mass index (BMI) would be used to measure the effect of acupuncture on obesity. According to the trial data extraction form based on the Cochrane Handbook, two reviewers separately extracted the data. Risk of bias of the RCTs was assessed by the Cochrane Risk of Bias Tool. The study included 8 RCTs with 403 patients. When compared with sham acupuncture, acupuncture showed obviously effect in BMI reduction (MD=1.0kg/m2, 95% CI=0.6 to 1.4, P<0.001). There was also significant reduction in body weight (MD=1.85kg, 95%CI=0.82 to 2.88, p<0.001), WC (MD=0.97cm, 95%CI=0.24 to 1.71, p=0.01) and body fat mass percentage (MD=1.01, 95%CI=0.25 to 1.77, p<0.05). However, WHR (MD=0.01, 95%CI=0 to 0.03, p>0.05) was not statistically and significantly different between the acupuncture and control groups. Adverse effects were reported in 3 studies. The review suggests that acupuncture is an effective therapy for simple obesity rather than a placebo effect. This potential benefit needs to be further evaluated by longer-term and more rigorous RCTs.

  • complementary medicine
  • information management
  • public health

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  • Contributors Y-MZ, H-YZ and D-LL contributed to the conception and design of the study. Y-MZ drafted the manuscript. W-TL and Y-NS carried out the the data extraction and statistical analysis. H-YZ and YC provided critical insights. X-CL and L-LZ reviewed the manuscript. All authors have read and approved the final submitted version of this protocol.

  • Funding This work was supported by grants from the National Natural Science Foundation of China (No. 81674068 and No. 81973959).

  • Competing interests None declared.

  • Patient consent for publication Not required.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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