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A man in his 40s presented to us with generalised erosions for past 3 days (figure 1A,B). He was diagnosed with psoriasis and initiated on weekly low-dose (15 mg) oral methotrexate a few days back. Two weeks after starting the treatment, he noticed bleeding from pre-existing plaques of psoriasis on cubital fossa. Thereafter, he developed multiple erosions on normal skin as well as on pre-existing plaques, in generalised distribution. Additionally, he noticed oral and genital erosions associated with bleeding and burning. The eruption was not preceded by vesicles or any systemic features. Apart from methotrexate, the patient was taking folic acid 5 mg weekly.
A physical examination revealed multiple erosions predominantly affecting the body folds, lumbosacral area, lower limbs, palms and soles in a symmetrical pattern. …
Contributors Each author has contributed sufficiently. RB diagnosed the case. RB, DC and NH managed the case and wrote the manuscript. PJ provided histopathological diagnosis and images.
Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.
Competing interests None declared.
Patient consent for publication Obtained.
Provenance and peer review Not commissioned; externally peer reviewed.
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