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Delayed-type hypersensitivity reaction to enoxaparin in a pregnant woman
  1. Garima Dabas1,
  2. Dipankar De1,
  3. Sanjeev Handa1,
  4. Divya Aggarwal2
  1. 1 Dermatology, Venereology and Leprology, Post Graduate Institute of Medical Education and Research, Chandigarh, India
  2. 2 Histopathology, Post Graduate Institute of Medical Education and Research, Chandigarh, India
  1. Correspondence to Dr Dipankar De, Post Graduate Institute of Medical Education and Research, Chandigarh 160012, India; dr_dipankar_de{at}

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A 32-year-old pregnant woman (G5P0L0A4) presented at 10+ weeks of gestation with multiple itchy plaques of 3 weeks duration. She was a known case of antiphospholipid antibody syndrome and was on treatment with low molecular weight heparin (LMWH, enoxaparin) and aspirin since past 4 weeks. On examination, multiple erythematous, indurated plaques were present on the abdomen (figure 1A) and both upper thighs. The lesions were restricted to the sites of subcutaneous enoxaparin injections. Histopathology of the …

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  • Contributors GD, DD and SH had full access to all the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis. DD contributed to the study concept and design. GD drafted the manuscript. DD and SH critical revised the manuscript for important intellectual content. All the authors contributed to the acquisition, analysis and interpretation of data.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent for publication Obtained.

  • Provenance and peer review Not commissioned; internally peer reviewed.

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