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Delayed-type hypersensitivity reaction to enoxaparin in a pregnant woman
  1. Garima Dabas1,
  2. Dipankar De1,
  3. Sanjeev Handa1,
  4. Divya Aggarwal2
  1. 1 Dermatology, Venereology and Leprology, Post Graduate Institute of Medical Education and Research, Chandigarh, India
  2. 2 Histopathology, Post Graduate Institute of Medical Education and Research, Chandigarh, India
  1. Correspondence to Dr Dipankar De, Post Graduate Institute of Medical Education and Research, Chandigarh 160012, India; dr_dipankar_de{at}yahoo.in

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A 32-year-old pregnant woman (G5P0L0A4) presented at 10+ weeks of gestation with multiple itchy plaques of 3 weeks duration. She was a known case of antiphospholipid antibody syndrome and was on treatment with low molecular weight heparin (LMWH, enoxaparin) and aspirin since past 4 weeks. On examination, multiple erythematous, indurated plaques were present on the abdomen (figure 1A) and both upper thighs. The lesions were restricted to the sites of subcutaneous enoxaparin injections. Histopathology of the …

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