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What is the most appropriate treatment for chronic rhinosinusitis?
  1. Abigail Walker1,
  2. Carl Philpott2,
  3. Claire Hopkins1
  1. 1 Guy's and Saint Thomas' Hospitals NHS Trust, London, UK
  2. 2 James Paget University Hospitals NHS Foundation Trust, Great Yarmouth, UK
  1. Correspondence to Abigail Walker, Guy's and Saint Thomas' Hospitals NHS Trust, London, UK; abigail.walker{at}


Chronic rhinosinusitis (CRS) is a common, treatable disease that affects approximately 11% of British adults. It places an enormous burden on patients, with significant detriment to their quality of life, and the health service as it consumes vast numbers of both primary and secondary care resources. However, there is considerable variability in treatment strategies and prescribing practices. This review summarises the key recommendations from landmark guidelines in the treatment of CRS and critically appraises the evidence for treatment.

  • sinusitis
  • rhinitis
  • antibiotics
  • nasal surgery
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  • Contributors All three authors contributed equally to this article with review of evidence, writing the text, and editing the whole piece.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests CH and CP are the chief investigators of the NIHR funded "MACRO" trial.

  • Patient consent for publication Not required.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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