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Contributors TU wrote the manuscript. TU, MI, AA, CS and MT were involved in patient management and collection of data. TU, MI, AA, CS and MT edited and approved the final manuscript.
Funding The authors did not receive government research grants to carry out the present study nor they did receive any funding from the commercial or not-for-profit sectors.
Competing interests None declared.
Patient consent for publication Obtained.
Provenance and peer review Not commissioned; externally peer reviewed.
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