Article Text

Download PDFPDF
Generalised lentiginosis and café noir spots leading to a diagnosis of LEOPARD syndrome
  1. Ankur Guliani1,
  2. Sheetanshu Kumar1,
  3. Dipankar De1,
  4. Divya Aggarwal2,
  5. Bishan Dass Radotra2
  1. 1 Department of Dermatology, Venereology and Leprology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
  2. 2 Department of Histopathology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
  1. Correspondence to Dr. Dipankar De, Department of Dermatology, Venereology and Leprology, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India; dr_dipankar_de{at}yahoo.in

Statistics from Altmetric.com

Dermatology consultation was sought for a 15-year-old boy with generalised lentiginosis since infancy (figure 1A). He also had darkly pigmented, irregular, larger lesions up to 2 cm in size suggestive of café noir spots1 (figure 1B).

Figure 1

(A) Multiple darkly pigmented macules all over the body suggestive of lentigines. (B) Well-defined, darkly pigmented, irregular patches, larger in size up to 2 cm suggestive of café noir spots.

Dermoscopy revealed pigment network, black dots and dark globules (figure 2A). He also had facial dysmorphism, low set ears, significant growth retardation and below average IQ of 82. Puberty was not attained yet in the patient …

View Full Text

Footnotes

  • Contributors AG and DD had full access to all of the data in the study and take responsibility for the integrity of the data and the accuracy of the data analysis. Study concept and design: AG and SK. Acquisition, analysis and interpretation of data: DA, BDR, SK and AG. Drafting of the manuscript: AG, SK and DD. Critical revision of the manuscript for important intellectual content: DD and BDR.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Patient consent Parental/guardian consent obtained.

  • Provenance and peer review Not commissioned; internally peer reviewed.

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.