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Interventions for smoking cessation in patients admitted with Acute Coronary Syndrome: a review
  1. Omar M Chehab1,2,
  2. Habib A Dakik1
  1. 1 Division of Cardiology, Department of Internal Medicine, American University of Beirut Medical Center, Beirut, Lebanon
  2. 2 National Heart and Lung Institute, Faculty of Medicine, Imperial College London, London, UK
  1. Correspondence to Dr Omar M Chehab, Preventive Cardiology, Imperial College London, Post-Doctoral Research Fellow, American University of Beirut Medical Center, Beirut 11-0236, Lebanon; omarshehab1991{at}


Tobacco smoking contributes to about six million deaths per year and is predicted to increase in the future. Several pharmacological interventions are used for smoking cessation. Trials using nicotine replacement therapy (NRT) in acute coronary syndrome (ACS) showed inconclusive results. Furthermore, three trials using bupropion in patients admitted with ACS failed to show improvement in smoking cessation compared with placebo. Interestingly, only one trial using varenicline was successful in achieving smoking abstinence in the acute setting. With regard to behavioural interventions, a meta-analysis found that telephone counselling was successful in both the acute and stable settings, with greater effect in the acute setting. The best results for smoking cessation were found in trials that used a combination of pharmacological and behavioural interventions. The objective of this report is to review the results of studies on interventions used for smoking cessation after an ACS.

  • Smoking cessation
  • Hospitalized
  • Bupropion
  • Varenicline
  • Nicotine Replacement Therapy
  • Behavioral interventions.

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  • Contributors OMC conceived the study, contributed to the design of the study and drafted the manuscript. HAD contributed to the revision of the final manuscript. Both authors read and approved the final version of the manuscript.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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