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Recent advances in the treatment of erectile dysfunction
  1. David F Mobley1,
  2. Mohit Khera2,
  3. Neil Baum3
  1. 1 Department of Urology, Weill-Cornell Medicine, Houston, Texas, USA
  2. 2 Department of Urology, Baylor College of Medicine, Houston, Texas, USA
  3. 3 Department of Urology, Tulane Medical School, New Orleans, Louisiana, USA
  1. Correspondence to Dr David F Mobley, Department of Urology, Weill-Cornell Medicine, 18300 Katy Fwy, Ste 325, Houston 77094, TX, USA; mobleyresearch{at}


Erectile dysfunction (ED) is one of the most common conditions affecting middle-aged and older men. Nearly every primary care physician, internist and geriatrician will be called upon to manage this condition or to make referrals to urologists, endocrinologists and cardiologists who will assist in the treatment of ED. This article will briefly discuss the diagnosis and management of ED. In addition, emerging concepts in ED management will be discussed, such as the use of testosterone to treat ED, the role of the endothelium in men with ED and treating the partner of the man with ED. Finally, future potential therapies for ED will be discussed.

  • erectile dysfunction
  • endothelial dysfunction
  • testosterone
  • testosterone deficiency
  • androgen deficiency
  • testosterone replacement
  • cardiovascular disease
  • stem cells
  • gene therapy

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  • Contributors DFM and NB wrote the majority of the manuscript. MK wrote the section on testosterone and made review comments and approved the final manuscript along with the attached figure.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.