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Reverse Tako-tsubo cardiomyopathy: a clinical entity mimicking acute coronary syndrome
  1. Bartosz Olechowski,
  2. Simon J Corbett,
  3. Benoy N Shah
  1. Wessex Cardiothoracic Centre, University Hospital Southampton NHS Foundation Trust, Southampton, Hampshire, UK
  1. Correspondence to Dr Bartosz Olechowski, Cardiac Administration Offices, Level E North Wing, Southampton General Hospital, Tremona Road, Southampton, Hampshire SO16 6YD, UK; bartosz.olechowski{at}

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Tako-Tsubo cardiomyopathy (TC) is an increasingly well-recognised condition that mimics acute coronary syndrome and is characterised by transient left ventricular (LV) systolic dysfunction without significant coronary artery disease. In recent years, three main variants of TC have emerged: the typical pattern, the reverse pattern and the apical sparing pattern. In typical TC, the LV apex balloons and the apical segments are akinetic (non-contractile) and, to compensate, the basal segments display hyperdynamic function. In reverse TC, there is basal segment akinesia but with normal apical function.


A 56-year-old woman returned from holiday to find that her home had been burgled. Soon after this unfortunate discovery, she developed severe left sided chest pain with breathlessness, nausea and sweating. The pain was unaffected by position or posture and her anterior chest wall was not tender to palpation. She had no …

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  • Contributors All authors took part in writing the manuscript and accepted the final version.

  • Competing interests None declared.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.