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Evolving role of cardiac CT in the diagnosis of coronary artery disease
  1. Ajay Yerramasu1,
  2. Shreenidhi Venuraju1,
  3. Avijit Lahiri1,2,3
  1. 1Clinical Imaging and Research Centre, Wellington Hospital, London, UK
  2. 2Middlesex University, London, UK
  3. 3Imperial College, London, UK
  1. Correspondence to Dr Ajay Yerramasu, Clinical Imaging and Research Centre, Wellington Hospital, London NW8 9LE, UK; dryerramasu{at}


Non-invasive assessment of coronary artery patency has been attempted with different imaging modalities over the last few decades. The continuous motion of the heart, the respiratory movement, together with the small and tortuous nature of the coronary arteries, made this a technically challenging task. Over the last decade, significant advances in computed tomography (CT) technology helped CT coronary angiography (CTCA) to evolve as a non-invasive alternative to conventional catheter based coronary angiography. Clinical experience with CTCA has since grown rapidly and led to its acceptance as a useful diagnostic technique for coronary artery disease in certain patient populations. Recently, there has been exponential growth in the availability and use of CTCA in several centres across the world. In order to appreciate the potential impact of CTCA on current clinical practice, it is important to understand its advantages and limitations and its clinical performance in comparison with established techniques.

  • Coronary heart disease
  • ischaemic heart disease
  • cardiology
  • cardiovascular imaging
  • CT

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  • Competing interests None.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.