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What’s being used to spike your drink? Alleged spiked drink cases in inner city London
  1. S L Greene1,
  2. C M Shiew1,
  3. P Streete2,
  4. S J Mustchin2,
  5. D Hugget3,
  6. B Earl2,
  7. P I Dargan1
  1. 1
    Guys and St Thomas’ Poisons Unit, Guys and St Thomas’ NHS Foundation Trust, London, UK
  2. 2
    Medical Toxicology Laboratory, Guys and St Thomas’ NHS Foundation Trust, London, UK
  3. 3
    Emergency Department, Guys and St Thomas’ NHS Foundation Trust, London, UK
  1. Dr P Dargan, Medical Toxicology Unit, Avonley Rd, New Cross, London SE14 5ER, UK; Paul.Dargan{at}


Objectives: To determine the incidence and character of drink spiking in an urban population of patients within the UK presenting to an emergency department concerned they had consumed a deliberately contaminated drink.

Study design: Prospective case series determining the presence and quantity of sedative and illicit drugs, and ethanol in biological samples (blood and urine) obtained from consenting patients >18 years of age presenting to a large inner city London emergency department alleging they had consumed a spiked drink within the previous 12 h.

Results: Biological samples were obtained from 67 (blood) and 75 (urine) of 78 study participants. 82% of participants were female, mean age 24 years. Mean time from alleged exposure to biological sampling was 5.9 h (range 1–12 h). Ethanol was detected in 89.7% of participants. Mean serum ethanol concentration was 1.65 g/l (range 0.04–3.1 g/l); 60% of participants had a serum ethanol concentration associated with significant intoxication (>1.5 g/l). Illicit drugs were detected in 12 (15%) participants; 7 denied intentional exposure (3 methylenedioxymethamphetamine, 3 cannabis, 1 γ-hydroxybutyrate). Medicinal drugs were detected in 13 participants; only 1 exposure was unexplained (benzodiazepine). Overall illicit or medicinal drugs of unexplained origin were detected in 8 (10%) participants. Unexplained sedative drug exposure was detected in only 2 (3%) participants.

Conclusions: Use of sedative drugs to spike drinks may not be as common as reported in the mainstream media. A large number of study participants had serum ethanol concentrations associated with significant intoxication; the source (personal over-consumption or deliberate drink spiking) is unclear.

  • spiked drink
  • illicit drugs
  • ethanol
  • poisoning
  • unlawful

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  • Competing interests: None.

  • Ethics approval: The St Thomas’ Hospital COREC committee provided ethical approval for this study (St Thomas’ Hospital COREC, Guys and St Thomas’ NHS Foundation Trust, Lambeth Palace Rd, London SE1 7EH, UK)

  • Abbreviations:
    drug facilitated sexual assault
    emergency department