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NT-proBNP and the diagnosis of left ventricular systolic dysfunction within two acute NHS trust catchment areas: the initial Teesside experience
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    confounding factors when defining the cut-off level for NT-pro BNP

    Dear editor

    The cut off level for NT-pro BNP proposed by the authors(1) should take into account the fact that blood levels of this parameter may be lower in subjects with body mass index equal to or exceeding 30 kg/metre squared despite left ventricular end diastolic pressures which exceed those of counterparts with lower body mass indices(2). Lower cut-off levels might then have to be devised in obese subjects....

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    Conflict of Interest:
    None declared.