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Cryoglobulinaemic vasculitis: classification and clinical and therapeutic aspects

Abstract

Cryoglobulinaemia may cause cutaneous vasculitis and glomerulonephritis, potentially leading to end stage renal failure. An important proportion of cryoglobulinaemias are secondary to hepatitis C virus infection. Emerging antiviral treatment options offer a chance for causal therapy of these cases of cryoglobulinaemia. This review summarises the classification and clinical and therapeutic aspects of cryoglobulinaemic vasculitis and glomerulonephritis.

  • ANCA, antineutrophil cytoplasmic antibody
  • HBV, hepatitis B virus
  • HCV, hepatitis C virus
  • MPGN, membranoproliferative glomerulonephritis

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