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Management of acute renal failure


Acute renal failure is a common condition, frequently encountered in both community practice and hospital inpatients. While it remains a heterologous condition, following basic principles makes investigation straightforward, and initial management follows a standard pathway in most patients. This article shows this, advises on therapeutic strategies, including those in special situations, and should help the clinician in deciding when to refer to a nephrologist, and when to consider renal replacement therapy.

  • ARF, acute renal failure
  • ATN, acute tubular necrosis
  • AIN, acute interstitial nephritis
  • GFR, glomerular filtration rate
  • NSAID, non-steroidal anti-inflammatory drug
  • ACE-I, angiotensin converting enzyme inhibitors
  • ARB, angiotensin receptor blockers
  • RRT, renal replacement therapy
  • CRRT, continuous renal replacement therapy
  • RPGN, rapidly progressive glomerulonephritis
  • acidosis
  • acute renal failure
  • dialysis
  • hyperkalaemia

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