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Under-recognised paradox of neuropathy from rapid glycaemic control
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  • Published on:
    Neuropathy by overachieved rapid glycemic oral control
    • San M, Engineer Patient self

    Letter response to the article "Under-recognised paradox of neuropathy from rapid glycaemic control."

    I am a data point of what the author says is elusive example of neuropathy (albeit in initial stages) by rapid glycemic control using only oral medication.
    My A1c reduced by about 1 point ( 7.7 to 6.8) in 3 months and further down to 6.1 in 3 more subsequent months.

    From the initial 7.7 A1c date, I was started on a higher oral dosage, as well as serious diet modification.

    Two months later, I had a rapid onset of feet burning symptoms. The symptoms came on and off. With subsequent tighter diet control that included episodes of low glucose levels, feet burning was still present and became more frequent. After reading up on this subject and its counter intuitive conclusions, I loosened diet control and also had my doctor reverse the last medication increase to previous levels. This seems to have helped and my left foot has been free of burning for a few days now, and the right foot also improving. Continuing monitoring and hoping for the best. Thanks to your and similar articles for highlighting this controversial and elusive phenomenon.

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    Conflict of Interest:
    None declared.
  • Published on:
    Grounds for abandoning "diabetes" as a diagnosis?

    Dear Editor,

    Unlike peripheral tissues where insulin promotes, and indeed is necessary for cellular glucose uptake and utilisation, that is not true for the brain and presumably, therefore, peripheral nerves. The inference is that changes in the rate of glucose uptake by the brain and peripheral nerves are a function of its concentration in blood and are driven by mass action independently of insulin. In which ca...

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    Conflict of Interest:
    None declared.