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Drug therapy in chronic heart failure
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  • Published on:
    "Permissive Hypotension" in Hibernated Patients with Severe Chronic Heart Failure

    Dear Editor

    Heart failure is a complex clinical syndrome that can result from any structural or functional cardiac abnormality that impairs the ability of the left ventricle to fill with or pump blood.

    The cardinal manifestations of heart failure are dyspnoea and fatigue, which may limit exercise tolerance, and fluid retention, which may lead to pulmonary congestion and peripheral oedema. Heart failure is cha...

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    Conflict of Interest:
    None declared.
  • Published on:
    Is "triple" therapy for heart failure validated ?

    Dear Editor

    We read the comprehensive review on drug treatment of heart failure by McKenzie and Cowley with great interest.[1]

    While they appropriately state the efficacy of the ACE inhibitor/beta-blocker and ACE inhibitor/spironolactone combinations in systolic heart failure, the average reader may get the impression that all three drugs can be used together in a patient. The article fails to clarify f...

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    Conflict of Interest:
    None declared.