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Adverse drug reactions
Clozapine associated dilated cardiomyopathy
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  • Published on: 18 November 2003
    Clozapine associated with myocarditis and cardiomyopathy
    • Detlef Degner, MD
    • Other Contributors:
      • Borwin Bandelow, Renate Grohmann, and Eckart Rüther

    Dear Editor

    In their article, Tanner and Culling describe the risk of cardiomyopathy in clozapine treatment.[1] Kilian et al.[2] reported about 15 patients with myocarditis and cardiomyopathy out of 8000 patients treated with clozapine (0.178%) in Australia. In the European Drug Safety Program (AMSP) in Germany,Austria , and Switzerland,3 cases of myocarditis among 10,263 monitored patients with clozapine therapy...

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    Conflict of Interest:
    None declared.