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The differential diagnosis of JME should have mentioned specifically
Sub-acute Scerosing Pan Encephalitis (SSPE), although progressive
myoclonic epilepsies have been mentioned. SSPE occurs in India as measles
still occurs and the age for first symptom of SSPE is similar to that of
JME. SSPE carries a poor prognosis but JME responds to sodium valproate.
The diagnosis of SSPE is based in clin...
The diagnosis of SSPE is based in clinical settings in India on EEG,
myoclonus, early dementia and past history of measles, which may be
elicited as measles was common but may not be aetiological factor in a
patient of JME.
We fear if a patient of JME is misdiagnosed as SSPE then upon hearing
a poor prognosis the parents may not return for follow-up or discontinue
(whatever) medications given.