Article Text
Statistics from Altmetric.com
Troponin T blood concentrations are raised, not only in lobar pneumonia,1 but also in submassive pulmonary embolism.2 I hypothesise that this phenomenon is mediated by endothelial damage in the pulmonary vasculature, which has an abundance of angiotensin converting enzyme (ACE).3 Derangements in the renin/angiotensin/aldosterone system (RAAS), in which ACE plays a pivotal part, may, in turn, affect troponin blood concentrations, given the interdependence between the RAAS and troponin release.4 The latter was exemplified by a study documenting the inhibition of troponin release as a result of ACE blockade in patients with acute coronary syndromes characterised by non-ST segment elevation.4
Request Permissions
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.