Clinical implications of the specialised B cell response to polysaccharide encapsulated pathogens

C G Vinuesa; C de Lucas; M C Cook

doi:10.1136/pmj.77.911.562

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Clinical implications of the specialised B cell response to polysaccharide encapsulated pathogens

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	Abstract	Full	Pdf
Aug 2001	0	28	3
Sep 2001	0	42	10
Oct 2001	0	26	6
Nov 2001	0	16	8
Dec 2001	0	9	2
Jan 2002	0	13	2
Feb 2002	0	17	6
Mar 2002	0	5	3
Apr 2002	0	22	10
May 2002	0	15	15
Jun 2002	0	3	1
Jul 2002	0	19	5
Aug 2002	0	10	6
Sep 2002	0	2	0
Oct 2002	0	16	0
Nov 2002	0	10	6
Dec 2002	0	6	4
Jan 2003	0	4	0
Feb 2003	0	9	3
Mar 2003	0	8	3
Apr 2003	0	4	4
May 2003	0	8	2
Jun 2003	0	5	1
Jul 2003	0	47	0
Aug 2003	0	10	0
Sep 2003	0	11	1
Oct 2003	0	52	0
Nov 2003	0	14	10
Dec 2003	0	10	3
Jan 2004	0	63	0
Feb 2004	0	9	0
Mar 2004	0	16	4
Apr 2004	0	15	2
May 2004	0	42	29
Jun 2004	0	45	6
Jul 2004	0	69	13
Aug 2004	0	113	36
Sep 2004	0	158	19
Oct 2004	15	95	13
Nov 2004	16	109	20
Dec 2004	6	68	11
Jan 2005	13	84	17
Feb 2005	3	54	13
Mar 2005	18	42	7
Apr 2005	5	75	15
May 2005	1	49	15
Jun 2005	1	44	30
Jul 2005	4	58	4
Aug 2005	3	77	19
Sep 2005	2	64	11
Oct 2005	4	72	23
Nov 2005	9	81	26
Dec 2005	6	49	9
Jan 2006	5	77	6
Feb 2006	5	70	21
Mar 2006	1	54	5
Apr 2006	6	49	18
May 2006	2	47	14
Jun 2006	3	30	7
Jul 2006	0	42	4
Aug 2006	1	36	8
Sep 2006	10	59	20
Oct 2006	4	87	19
Nov 2006	5	60	16
Dec 2006	5	35	14
Jan 2007	3	48	17
Feb 2007	1	45	27
Mar 2007	6	44	17
Apr 2007	28	20	20
May 2007	25	23	19
Jun 2007	16	13	10
Jul 2007	11	17	15
Aug 2007	8	11	10
Sep 2007	24	9	13
Oct 2007	19	11	10
Nov 2007	23	21	14
Dec 2007	15	10	7
Jan 2008	12	14	14
Feb 2008	23	7	15
Mar 2008	20	14	19
Apr 2008	26	10	13
May 2008	16	12	11
Jun 2008	20	14	16
Jul 2008	14	9	8
Aug 2008	22	19	10
Sep 2008	49	14	11
Oct 2008	42	17	9
Nov 2008	38	8	7
Dec 2008	15	7	3
Jan 2009	28	12	10
Feb 2009	29	11	8
Mar 2009	34	10	13
Apr 2009	20	11	10
May 2009	18	21	6
Jun 2009	18	12	5
Jul 2009	11	7	4
Aug 2009	7	7	4
Sep 2009	17	7	12
Oct 2009	16	6	12
Nov 2009	18	10	9
Dec 2009	12	5	2
Jan 2010	15	7	4
Feb 2010	17	10	9
Mar 2010	13	12	3
Apr 2010	14	10	5
May 2010	8	5	5
Jun 2010	9	5	6
Jul 2010	5	1	2
Aug 2010	60	28	2
Sep 2010	123	81	10
Oct 2010	137	60	5
Nov 2010	146	96	7
Dec 2010	95	60	3
Jan 2011	182	58	12
Feb 2011	207	68	5
Mar 2011	260	102	9
Apr 2011	172	52	0
May 2011	172	41	4
Jun 2011	196	46	1
Jul 2011	193	21	6
Aug 2011	247	34	1
Sep 2011	270	50	7
Oct 2011	262	93	8
Nov 2011	172	112	7
Dec 2011	30	259	13
Jan 2012	23	229	18
Feb 2012	11	215	20
Mar 2012	11	213	12
Apr 2012	15	308	31
May 2012	27	393	19
Jun 2012	19	335	19
Jul 2012	32	242	30
Aug 2012	21	230	25
Sep 2012	19	264	27
Oct 2012	23	289	23
Nov 2012	0	153	14
Dec 2012	0	49	9
Jan 2013	0	84	11
Feb 2013	0	73	16
Mar 2013	0	91	16
Apr 2013	0	123	33
May 2013	0	99	13
Jun 2013	12	90	11
Jul 2013	19	56	2
Aug 2013	14	44	2
Sep 2013	12	45	9
Oct 2013	7	56	21
Nov 2013	7	48	10
Dec 2013	7	51	8
Jan 2014	13	31	15
Feb 2014	7	50	16
Mar 2014	10	44	5
Apr 2014	17	69	15
May 2014	14	93	6
Jun 2014	5	111	8
Jul 2014	9	116	12
Aug 2014	9	93	11
Sep 2014	9	109	42
Oct 2014	12	75	18
Nov 2014	4	119	9
Dec 2014	5	68	10
Jan 2015	4	64	12
Feb 2015	7	89	13
Mar 2015	14	70	12
Apr 2015	4	81	8
May 2015	2	73	8
Jun 2015	15	73	5
Jul 2015	3	39	11
Aug 2015	5	41	5
Sep 2015	14	95	8
Oct 2015	11	48	4
Nov 2015	11	98	16
Dec 2015	21	47	6
Jan 2016	15	67	8
Feb 2016	19	40	17
Mar 2016	22	67	18
Apr 2016	9	96	17
May 2016	7	79	16
Jun 2016	8	45	9
Jul 2016	12	58	8
Aug 2016	10	69	4
Sep 2016	18	60	14
Oct 2016	13	76	16
Nov 2016	16	117	20
Dec 2016	9	67	14
Jan 2017	2	48	8
Feb 2017	0	60	16
Mar 2017	0	70	15
Apr 2017	0	65	4
May 2017	0	137	23
Jun 2017	11	89	51
Jul 2017	27	27	13
Aug 2017	30	30	15
Sep 2017	144	142	24
Oct 2017	106	104	16
Nov 2017	131	132	24
Dec 2017	117	118	22
Jan 2018	135	135	15
Feb 2018	183	179	32
Mar 2018	128	126	55
Apr 2018	142	142	41
May 2018	133	132	20
Jun 2018	100	100	13
Jul 2018	96	94	37
Aug 2018	112	112	25
Sep 2018	154	154	37
Oct 2018	123	123	26
Nov 2018	166	166	38
Dec 2018	119	120	18
Jan 2019	143	142	13
Feb 2019	139	140	15
Mar 2019	121	121	21
Apr 2019	121	122	27
May 2019	175	171	23
Jun 2019	132	129	14
Jul 2019	113	112	17
Aug 2019	126	126	11
Sep 2019	164	162	22
Oct 2019	205	201	33
Nov 2019	201	201	14
Dec 2019	160	152	21
Jan 2020	162	160	20
Feb 2020	182	180	29
Mar 2020	172	172	23
Apr 2020	146	144	32
May 2020	286	278	101
Jun 2020	121	121	15
Jul 2020	131	131	26
Aug 2020	114	113	23
Sep 2020	202	198	29
Oct 2020	196	192	21
Nov 2020	228	221	24
Dec 2020	160	157	19
Jan 2021	157	153	31
Feb 2021	186	186	47
Mar 2021	211	211	21
Apr 2021	193	191	25
May 2021	169	176	15
Jun 2021	99	100	18
Jul 2021	161	163	39
Aug 2021	149	151	17
Sep 2021	230	234	31
Oct 2021	178	177	53
Nov 2021	99	99	24
Dec 2021	163	171	31
Jan 2022	180	182	21
Feb 2022	146	150	25
Mar 2022	219	217	32
Apr 2022	144	146	28
May 2022	197	184	29
Jun 2022	103	102	11
Jul 2022	103	104	20
Aug 2022	113	113	11
Sep 2022	153	151	15
Oct 2022	150	154	20
Nov 2022	123	125	15
Dec 2022	85	83	8
Jan 2023	95	95	21
Feb 2023	124	124	12
Mar 2023	109	105	12
Apr 2023	76	79	18
Total	14698	21479	3818

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