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Hypercalcaemia in a 63 year old man
  1. L Ranganatha,
  2. M J Sempleb
  1. aEpsom General Hospital, Epsom, Surrey UK: Department of Chemical Pathology, bDepartment of Haematology
  1. Dr L Ranganath, Department of Clinical Chemistry, Royal Liverpool University Hospital, Prescot Street, Liverpool L7 8XP, UK (e-mail:lrang{at}

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A 63 year old man with IgG myeloma was found to have hypercalcaemia; specific hypocalcaemic measures such as intravenous fluids and pamidronate 60 mg followed by 1.6 g of oral sodium clodronate daily in addition to antimyeloma agents such as prednisolone, Adriamycin, and carmustine were unsuccessful in restoring eucalcaemia (fig 1).

Figure 1

Profile of serum corrected calcium before and after treatment.

Blood test results while on treatment with clodronate are shown in table1.

Table 1

Blood test results while on treatment with clodronate


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