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Ciprofloxacin-induced bone marrow depression
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  1. Tarun Kumar Dutta,
  2. Bhawana A Badhe
  1. Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry 605 006, India

    Abstract

    Ciprofloxacin, a broad-spectrum fluoroquinolone antibacterial agent, is generally considered to be a safe drug. However, occasionally it may have life-threatening complications. Two instances of bone marrow failure following use of ciprofloxacin are reported. In one case, the bone marrow reverted to normal following withdrawal of the drug. In the other case, the patient succumbed to irreversible bone marrow depression leading to severe thrombocytopenia and uncontrolled bleeding. This could have been an idiosyncratic reaction.

    • ciprofloxacin
    • bone marrow depression
    • adverse drug reaction
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