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Treatment of vitamin D deficient osteomalacia may unmask autonomous hyperparathyroidism.
  1. A. V. Taylor,
  2. P. H. Wise
  1. Department of Endocrinology, Charing Cross Hospital, London, UK.


    Two cases of vitamin D deficient osteomalacia with secondary hyperparathyroidism are presented. In both cases treatment with vitamin D replacement therapy resulted in elevated calcium levels and a failure of parathormone levels to normalise, indicating autonomous parathyroid activity. Subsequent surgery in one case resulted in removal of a parathyroid adenoma. The importance of osteomalacia and its complications are discussed.

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