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The role of cell migration and microchimerism in the induction of tolerance after solid organ transplantation.
  1. R. M. Jindal,
  2. A. Sahota
  1. Department of Surgery, Indiana University School of Medicine, Indianapolis 46202, USA.


    A new hypothesis has been proposed which states that microchimerism is the basis for the clinical tolerance seen in long-term survivors of solid organ transplants. Efforts to enhance microchimerism include simultaneous infusion of bone marrow of donor origin and transplantation of a solid organ. Studies are in progress to verify the phenomenon of microchimerism and its role in clinical tolerance.

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