Article Text

Download PDFPDF

Treatment of hyperemesis gravidarum with the 5-HT3 antagonist ondansetron (Zofran).
  1. D. G. Tincello,
  2. M. J. Johnstone
  1. Department of Obstetrics and Gynaecology, Fazakerley Hospital, Liverpool, UK.


    Ondansetron is a 5-hydroxytryptamine receptor antagonist which is known to be a highly effective anti-emetic drug for chemotherapy-associated nausea and vomiting and for postoperative nausea. We report here a case where ondansetron was used in severe hyperemesis gravidarum to avoid parenteral nutrition. The drug was used intermittently in every trimester with no apparent adverse effects on mother or infant.

    Statistics from

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.