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Malignant transformation in a fatal case of giant cell tumour of the sacrum.
  1. J. P. Crew,
  2. M. Flannery,
  3. B. Manners,
  4. C. J. Coates
  1. Royal Surrey County Hospital, Guildford, UK.


    Most giant cell tumours can be treated by local surgery and only rarely are they life threatening. We report a case of a giant cell tumour of the sacrum causing irresectable and fatal small bowel obstruction following malignant transformation of the tumour. The role of radiotherapy in this transformation is discussed.

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