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Chronic hypothermia and water intoxication associated with a neurodegenerative disease.
  1. E. L. Corbett,
  2. S. Sisodiya,
  3. D. Sarkar
  1. Department of Medicine, Whittington Hospital, London, UK.


    We describe a 71 year old man with a neurodegenerative condition who developed chronic inappropriate antidiuretic hormone secretion and hypothermia resulting in recurrent episodes of impaired consciousness. This combination of abnormalities is attributable to hypothalamic disease and has not to our knowledge been previously reported with clearly documented antidiuretic hormone excess.

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