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Cerebral arteriovenous malformation in Noonan's syndrome.
  1. F. Schon,
  2. J. Bowler,
  3. M. Baraitser
  1. Department of Neurology, Atkinson Morley's Hospital, London, UK.


    Noonan's syndrome involves the association of multiple congenital abnormalities including neck webbing, pectus excavatum, facial anomalies with a variety of cardiac defects. In this paper the association of Noonan's syndrome with a large cerebral arteriovenous malformation is reported. Congenital cerebrovascular abnormalities are not a recognized feature of the syndrome. The paper also reviews previous reports of neurological associations with Noonan's syndrome, the commonest being mild intellectual impairment and ptosis.

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