Article Text


Lipoprotein lipase deficiency due to long-term heparinization presenting as severe hypertriglyceridaemia in pregnancy.
  1. G. F. Watts,
  2. J. Cameron,
  3. A. Henderson,
  4. W. Richmond
  1. Department of Endocrinology and Chemical Pathology, United Medical School of Guy's Hospital, London, UK.


    A case of severe hypertriglyceridaemia presenting in the third trimester of pregnancy in a woman on long-term heparin prophylaxis is described. The hypertriglyceridaemia was attributed to impaired clearance of triglyceride-rich lipoprotein particles secondary to heparin-induced reduction in the activity of the lipolytic enzyme, lipoprotein lipase.

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