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Anticoagulation instability with life-threatening complication after dietary modification.
  1. W. H. Chow,
  2. T. C. Chow,
  3. T. M. Tse,
  4. Y. T. Tai,
  5. W. T. Lee
  1. Department of Medicine, Grantham Hospital, Aberdeen, Hong Kong.


    Anticoagulation instability due to a change in intake of vitamin K after dietary modification was observed in 2 patients on long-term oral anticoagulants. One patient developed diffuse bruises treated conservatively with fresh frozen plasma transfusion and the other had a thrombosed aortic prosthesis which required emergency operation. To prevent such complications, dietary modification especially with food rich in vitamin K should be undertaken with care in patients on long-term oral anticoagulants.

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