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Subungual amelanotic melanoma: a diagnostic pitfall.
  1. M. Winslet,
  2. J. Tejan
  1. Department of Orthopaedics, General Hospital, Birmingham, UK.


    A 35 year old female presented with a persistent amelanotic lesion of the nail bed of the left great toe for 1 year, associated with destruction of the overlying nail. Incision biopsy revealed a nodular malignant melanoma and the toe was amputated. There is no sign of recurrence at 18 month follow-up. As prognosis is related to local disease extent, any persistent nail bed lesion should be biopsied to exclude the possibility of malignant melanoma.

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