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Microscopic polyarteritis: clinical features and treatment.
  1. H. Rodgers,
  2. J. A. Guthrie,
  3. A. M. Brownjohn,
  4. J. H. Turney
  1. Regional Renal Unit, General Infirmary Leeds, UK.


    The clinical features, treatment and survival of 36 patients with microscopic polyarteritis diagnosed between 1957-1988 have been reviewed. All had a focal segmental necrotizing glomerulonephritis on renal biopsy with evidence of a small vessel vasculitis. Most had a prodromal illness of less than 1 month. Severity of renal disease varied from microscopic haematuria which has a good prognosis to acute oliguric renal failure which carries a high mortality. The prognosis of microscopic polyarteritis can be improved if the condition is recognized early and treated with steroids and cyclophosphamide.

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