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Acquired immune deficiency syndrome without the recognized risk factors.
  1. M. Rademaker,
  2. R. H. Thomas,
  3. T. G. Provost,
  4. M. McEvoy,
  5. P. C. Grint,
  6. R. Heath,
  7. J. D. Kirby
  1. Department of Dermatology, St Bartholomew's Hospital, West Smithfield, London, UK.


    We report two cases of acquired immune deficiency syndrome (AIDS), apparently without the usual exposure factors, in whom a temporal association was detected after detailed epidemiological investigation. The index case, a 45 year old housewife, had provided terminal home-nursing care for a 33 year old African man, who died from an undiagnosed encephalitis. At that time she had fissures of the skin of both her hands. Review of post-mortem pathology specimens of the African man allowed a retrospective diagnosis of AIDS with cerebral toxoplasmosis to be made. The type of home-nursing care given by the index case was quite different from that normally provided by health care workers with the training and facilities to prevent the spread of infection.

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