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A cumulative dose comparison between salbutamol and fenoterol metered dose aerosols in asthmatic patients.
  1. D. Bellamy,
  2. A. Penketh
  1. Brompton Hospital, London, UK.


    The potency and side effects of salbutamol and fenoterol inhalers have been compared in 8 asthmatic patients using a dose response curve. There was no significant difference in the absolute or percentage increase in FEV1 with the two treatments, but fenoterol caused a significantly greater (P less than 0.01) increase in heart rate than did salbutamol. A greater degree of bronchodilatation was observed with increased doses and we suggest that regular higher doses may provide better bronchodilatation and control of asthma in selected patients.

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