Article Text


The glucagon test in obstructive and hepatocellular jaundice
  1. David A. Berstock,
  2. John R. Wood,
  3. Roger Williams


    The plasma glucose response to an intravenous bolus of glucagon was examined in patients with obstructive jaundice, hepatocellular jaundice and in healthy volunteers. Plasma glucose levels were determined before and at 15, 30 and 45 min after glucagon. The glucose response to glucagon differed markedly in the two patient groups with significantly higher plasma glucose values in the obstructive jaundice group.

    Measurement of blood glucose after intravenous glucagon provides a simple test to assist in the differential diagnosis of obstructive and hepatocellular jaundice.

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