α1-Antitrypsin can be shown to be polymorphic by starch gel electrophoresis. At present 19 different alleles are known which are inherited in an autosomal pattern and constitute the Pi system. In one phenotype called Pi type ZZ there is a virtual deficiency of plasma α1-antitrypsin and about 230 such babies are expected in England and Wales every year.
Statistics from Altmetric.com
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.