In a 14-year-old girl Wilson's disease was found to be the etiologic basis of an active liver cirrhosis diagnosed months previously. Specific therapy with D-penicillamine caused remarkable clinical and biochemical improvement. Repeated liver scans using 198Au revealed increased liver uptake of the 198Au while the size of the spleen decreased. It is proposed that repeated liver scintiscanning may provide another easily performed and safe test for evaluation of the effect of therapy in these patients.
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