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Adult nephrotic syndrome in Ibadan, Nigeria: a prospective study of 135 cases
  1. O. O. Akinkugbe,
  2. Mollie Hunton


    One hundred and thirty-five adult patients admitted into the medical wards with the nephrotic syndrome have been studied over a period of 3 years.

    The histopathology in eighty-one renal biopsies showed predominantly proliferative glomerulonephritis.

    Nine patients had filariasis and in six of these the microfilaria isolated was Loa loa. Six patients had malarial parasitaemia; of these, three had P. malariae infection. Urinary schistosomiasis was diagnosed in four patients.

    Twenty-seven patients were noted to be hypertensive and 104 patients had some degree of impairment of renal function. A total of nine deaths was recorded (6·7%) in the 3-year period.

    The significance of these results is discussed.

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