Five patients with purpura hyperglobulinaemia are reviewed. One patient developed ulcerative colitis; female members of this patient's family suffered from rheumatoid arthritis. The family showed immunoglobulin abnormalities.
Although the clinical picture of purpura hyperglobulinaemia and Henoch-Schönlein purpura can show some common features, the former may well be separated as a ‘disturbed-tolerance’ disease with a different prognosis.
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