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<title>Postgraduate Medical Journal</title>
<url>http://pmj.bmj.com/homepage/PMJ_95x60.gif</url>
<link>http://pmj.bmj.com</link>
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<item rdf:about="http://pmj.bmj.com/cgi/content/short/85/1009/561?rss=1">
<title><![CDATA[The resuscitation game continues: what is really going on?]]></title>
<link>http://pmj.bmj.com/cgi/content/short/85/1009/561?rss=1</link>
<description><![CDATA[]]></description>
<dc:creator><![CDATA[Doyal, L., Doyal, L., Sokol, D.]]></dc:creator>
<dc:date>Thu, 05 Nov 2009 10:01:51 PST</dc:date>
<dc:subject><![CDATA[Emergency medicine, End of life decisions (geriatric medicine), Interventional cardiology, End of life decisions (palliative care), Ethics, Legal and forensic medicine]]></dc:subject>
<dc:identifier>info:doi/10.1136/pgmj.2009.091538</dc:identifier>
<dc:title><![CDATA[The resuscitation game continues: what is really going on?]]></dc:title>
<dc:publisher>The Fellowship of Postgraduate Medicine</dc:publisher>
<prism:number>1009</prism:number>
<prism:volume>85</prism:volume>
<prism:endingPage>563</prism:endingPage>
<prism:publicationDate>2009-11-01</prism:publicationDate>
<prism:startingPage>561</prism:startingPage>
<prism:section>Editorials</prism:section>
</item>

<item rdf:about="http://pmj.bmj.com/cgi/content/short/85/1009/564?rss=1">
<title><![CDATA[Factors that influence decisions about cardiopulmonary resuscitation: the views of doctors and medical students]]></title>
<link>http://pmj.bmj.com/cgi/content/short/85/1009/564?rss=1</link>
<description><![CDATA[
<sec><st>Background:</st>
<p>A number of studies have explored doctors&rsquo; views and experiences of cardiopulmonary resuscitation (CPR), but to our knowledge there has been no research to identify the information that doctors take into account when they make decisions about CPR.</p>
</sec>
<sec><st>Purpose of study:</st>
<p>To investigate factors that influence decisions about CPR.</p>
</sec>
<sec><st>Study design:</st>
<p>Qualitative study involving six focus groups with 17 doctors and four medical students in Leicester, UK.</p>
</sec>
<sec><st>Results:</st>
<p>Doctors and medical students considered a number of factors important when making decisions about CPR&mdash;namely, the patient&rsquo;s diagnosis, prognosis, age, quality of life, the opinions of doctors and other medical staff, and the wishes of patients and relevant others. The relative importance of each of these factors varied significantly and was influenced by the doctors&rsquo; own beliefs and values.</p>
</sec>
<sec><st>Conclusions:</st>
<p>Doctors would benefit from greater support for their decision making in relation to resuscitation to reduce variability in clinical practice and to promote appropriate patient care. Identification of factors that influence doctors&rsquo; individual beliefs, attitudes and values towards resuscitation and improvement in the quality of patient communication may help to guide policy in this area.</p>
</sec>
]]></description>
<dc:creator><![CDATA[Tyrer, F, Williams, M, Feathers, L, Faull, C, Baker, I]]></dc:creator>
<dc:date>Thu, 05 Nov 2009 10:01:51 PST</dc:date>
<dc:subject><![CDATA[Patients, Interventional cardiology, Communication]]></dc:subject>
<dc:identifier>info:doi/10.1136/pgmj.2009.079491</dc:identifier>
<dc:title><![CDATA[Factors that influence decisions about cardiopulmonary resuscitation: the views of doctors and medical students]]></dc:title>
<dc:publisher>The Fellowship of Postgraduate Medicine</dc:publisher>
<prism:number>1009</prism:number>
<prism:volume>85</prism:volume>
<prism:endingPage>568</prism:endingPage>
<prism:publicationDate>2009-11-01</prism:publicationDate>
<prism:startingPage>564</prism:startingPage>
<prism:section>Ethics and law</prism:section>
</item>

<item rdf:about="http://pmj.bmj.com/cgi/content/short/85/1009/569?rss=1">
<title><![CDATA[A doctor's experience of resuscitation decision making for older patients: coping with change]]></title>
<link>http://pmj.bmj.com/cgi/content/short/85/1009/569?rss=1</link>
<description><![CDATA[
<p>There has been a dramatic change in the way that resuscitation decisions are made for older hospital inpatients in the UK. In less than 20 years many geriatric medicine wards have moved from an "opt-in" policy (where the default position is not to provide resuscitation) to a position where resuscitation is widely available to older patients and clinicians are much more reluctant to make "do not attempt cardiopulmonary resuscitation" decisions on medical grounds alone. The drivers for this change are rooted in societal changes rather than scientific or legal advances. Older patients are increasingly educated and have higher expectations of health care, while doctors are more commonly criticised and have progressively less "power" in the doctor&ndash;patient relationship. Doctors in the UK are struggling with the growing volume and complexity of guidelines about resuscitation, which can prove very tricky to enact within current resources and priorities. Many are feeling stressed and under equipped to cope with the ethical and legal dilemmas of resuscitation decision making. The solution lies in better undergraduate and postgraduate training which enhances skills (such as consultation skills and ethical reasoning) and not just knowledge of laws, principles and guidelines.</p>
]]></description>
<dc:creator><![CDATA[Bowker, L]]></dc:creator>
<dc:date>Thu, 05 Nov 2009 10:01:51 PST</dc:date>
<dc:subject><![CDATA[Interventional cardiology]]></dc:subject>
<dc:identifier>info:doi/10.1136/pgmj.2009.082990</dc:identifier>
<dc:title><![CDATA[A doctor's experience of resuscitation decision making for older patients: coping with change]]></dc:title>
<dc:publisher>The Fellowship of Postgraduate Medicine</dc:publisher>
<prism:number>1009</prism:number>
<prism:volume>85</prism:volume>
<prism:endingPage>572</prism:endingPage>
<prism:publicationDate>2009-11-01</prism:publicationDate>
<prism:startingPage>569</prism:startingPage>
<prism:section>Ethics and law</prism:section>
</item>

<item rdf:about="http://pmj.bmj.com/cgi/content/short/85/1009/572?rss=1">
<title><![CDATA["X marks the spot" is not a pleural guarantee]]></title>
<link>http://pmj.bmj.com/cgi/content/short/85/1009/572?rss=1</link>
<description><![CDATA[]]></description>
<dc:creator><![CDATA[Medford, A R L, Entwisle, J J]]></dc:creator>
<dc:date>Thu, 05 Nov 2009 10:01:51 PST</dc:date>
<dc:subject><![CDATA[Journalology, Haematology (incl blood transfusion), Drugs: cardiovascular system, Radiology, Clinical diagnostic tests, Radiology (diagnostics), Ethics]]></dc:subject>
<dc:identifier>info:doi/10.1136/pgmj.2009.088286</dc:identifier>
<dc:title><![CDATA["X marks the spot" is not a pleural guarantee]]></dc:title>
<dc:publisher>The Fellowship of Postgraduate Medicine</dc:publisher>
<prism:number>1009</prism:number>
<prism:volume>85</prism:volume>
<prism:endingPage>572</prism:endingPage>
<prism:publicationDate>2009-11-01</prism:publicationDate>
<prism:startingPage>572</prism:startingPage>
<prism:section>Images in medicine</prism:section>
</item>

<item rdf:about="http://pmj.bmj.com/cgi/content/short/85/1009/573?rss=1">
<title><![CDATA[Invasive zygomycosis in India: experience in a tertiary care hospital]]></title>
<link>http://pmj.bmj.com/cgi/content/short/85/1009/573?rss=1</link>
<description><![CDATA[
<sec><st>Aim:</st>
<p>To report the natural history and clinical course of zygomycosis from a single tertiary care centre in India where doctors maintain an institutional zygomycosis registry.</p>
</sec>
<sec><st>Methods:</st>
<p>The clinical and laboratory data collected prospectively from patients with antemortem diagnosis for invasive zygomycosis, and retrospectively from autopsy diagnosed cases, over an 18 month period (July 2006&ndash;December 2007) were combined and analysed.</p>
</sec>
<sec><st>Results:</st>
<p>During the period 75 cases (50 cases/year) of zygomycosis were reported. Antemortem diagnosis could be made in 81% of cases and 9% of patients had nosocomial zygomycosis. The spectrum of disease included rhino-orbito-cerebral (48%), pulmonary (17%), gastrointestinal (13%), cutaneous (11%), renal and disseminated zygomycosis (5% each). Uncontrolled type 2 diabetes (58%) and diabetic ketoacidosis (38%) in the rhino-orbito-cerebral type, renal failure (69%) in the pulmonary type, prematurity (70%) in the gastrointestinal type, and breach of skin (88%) in cutaneous zygomycosis, were the significant (p&lt;0.05) underlying illnesses. <I>Rhizopus oryzae</I> (69%) was the most common isolate followed by <I>Apophysomyces elegans</I> (19%). Overall mortality was 45% in patients who could be treated. Outcome was significantly poor when surgical debridement could not be performed or the patients were treated only with amphotericin B deoxycholate. On multivariate analysis, patients with a Glasgow Coma Score (GCS) &gt;=9 had a better prognosis.</p>
</sec>
<sec><st>Conclusions:</st>
<p>Zygomycosis is a threat in uncontrolled diabetes. New risk factors such as renal failure and chronic liver disease require attention. <I>A elegans</I> is an emerging agent in India. The need for surgical debridement in addition to medical treatment is emphasised. GCS is an independent marker of prognosis in cases of invasive zygomycosis.</p>
</sec>
]]></description>
<dc:creator><![CDATA[Chakrabarti, A, Chatterjee, S S, Das, A, Panda, N, Shivaprakash, M R, Kaur, A, Varma, S C, Singhi, S, Bhansali, A, Sakhuja, V]]></dc:creator>
<dc:date>Thu, 05 Nov 2009 10:01:51 PST</dc:date>
<dc:subject><![CDATA[Liver disease, Urology, Statistics and research methods, Drugs: infectious diseases, Epidemiology, Diabetes, Metabolic disorders]]></dc:subject>
<dc:identifier>info:doi/10.1136/pgmj.2008.076463</dc:identifier>
<dc:title><![CDATA[Invasive zygomycosis in India: experience in a tertiary care hospital]]></dc:title>
<dc:publisher>The Fellowship of Postgraduate Medicine</dc:publisher>
<prism:number>1009</prism:number>
<prism:volume>85</prism:volume>
<prism:endingPage>581</prism:endingPage>
<prism:publicationDate>2009-11-01</prism:publicationDate>
<prism:startingPage>573</prism:startingPage>
<prism:section>Original article</prism:section>
</item>

<item rdf:about="http://pmj.bmj.com/cgi/content/short/85/1009/582?rss=1">
<title><![CDATA[How well prepared are medical students for their first year as doctors? The views of consultants and specialist registrars in two teaching hospitals]]></title>
<link>http://pmj.bmj.com/cgi/content/short/85/1009/582?rss=1</link>
<description><![CDATA[
<sec><st>Objective:</st>
<p>To evaluate (1) the extent to which first year doctors (foundation year 1 doctors, F1s) in two teaching hospitals in the Trent Deanery were rated by specialist registrars (SpRs) and consultants as being well prepared for practice; (2) the importance ascribed by SpRs and consultants to the various items of core knowledge, skills and attitudes outlined in the publication of the General Medical Council, <I>Tomorrow&rsquo;s Doctors</I>.</p>
</sec>
<sec><st>Method:</st>
<p>SpRs and consultants were asked to rate: how well prepared F1s were in a range of items of core knowledge, skills and attitudes that a new medical graduate must possess as outlined in <I>Tomorrow&rsquo;s Doctors</I>; the importance for a new doctor of each item of core knowledge, skills and attitudes; and how well the medical school had prepared F1s in respect of key generic issues related to their practice.</p>
</sec>
<sec><st>Results:</st>
<p>In most of the items of core knowledge, skills and attitudes covering 8 of the 11 topic areas of <I>Tomorrow&rsquo;s Doctors</I>, F1s were seen as not prepared for starting work, especially in regard to clinical and practical skills and the more challenging communication skills. They were best prepared in asking for help and in basic communication skills.</p>
</sec>
<sec><st>Conclusions:</st>
<p>Overall, F1s in the study were not well prepared either to perform the tasks that await them or in terms of most of the specific background knowledge and skills necessary for the successful execution of those tasks. The level of preparedness raises important issues about medical training and transition from medical graduate to first year doctor. Further research is needed to determine whether this situation exists in other regions of the UK.</p>
</sec>
]]></description>
<dc:creator><![CDATA[Matheson, C, Matheson, D]]></dc:creator>
<dc:date>Thu, 05 Nov 2009 10:01:51 PST</dc:date>
<dc:identifier>info:doi/10.1136/pgmj.2008.071639</dc:identifier>
<dc:title><![CDATA[How well prepared are medical students for their first year as doctors? The views of consultants and specialist registrars in two teaching hospitals]]></dc:title>
<dc:publisher>The Fellowship of Postgraduate Medicine</dc:publisher>
<prism:number>1009</prism:number>
<prism:volume>85</prism:volume>
<prism:endingPage>589</prism:endingPage>
<prism:publicationDate>2009-11-01</prism:publicationDate>
<prism:startingPage>582</prism:startingPage>
<prism:section>Original article</prism:section>
</item>

<item rdf:about="http://pmj.bmj.com/cgi/content/short/85/1009/590?rss=1">
<title><![CDATA[Parkinson disease and impulse control disorders: a review of clinical features, pathophysiology and management]]></title>
<link>http://pmj.bmj.com/cgi/content/short/85/1009/590?rss=1</link>
<description><![CDATA[
<p>Impulse control disorders (ICDs) are a heterogeneous group of conditions involving repetitive, excessive and compulsive activities that interfere with life functioning. Examples are pathological gambling, compulsive shopping and hypersexuality. Over the last decade, ICDs have become increasingly recognised as being associated with Parkinson disease (PD), with the literature highlighting a link between dopamine replacement therapy and the development of ICDs. Patients who develop ICDs in the context of compulsive anti-Parkinsonian drug use are described as having dopamine dysregulation syndrome (DDS), which is associated with repetitive complex stereotyped behaviours called punding. Case&ndash;control and observational studies have further noted that patients with PD who develop ICDs are more likely to have younger-onset PD, a history of alcohol dependence, novelty-seeking personality traits and psychiatric comorbidities. The pathophysiology of underlying mechanisms is not fully understood, but recent evidence suggests that dopaminergic drugs, particularly dopamine agonists, coupled with changes in reward pathways involving the ventral striatal and related circuitry, may play a role. Neuroimaging studies using positron emission tomography and functional MRI have provided valuable information in this area: patients with DDS have been found to show enhanced dopamine release in the ventral striatum, suggesting functional abnormalities in the mesolimbic networks. Management of ICDs in patients with PD can be challenging, as they may not be aware of a change in their behaviour or may conceal their symptoms to avoid embarrassment. Currently, there is no clear evidence of an optimal treatment. Management is based on a careful balance of dopaminergic drugs with control of the aberrant behaviour, supported by psychological interventions. This review aims to summarise the current literature on ICDs, their phenomenology, epidemiology, clinical features, pathophysiology and management.</p>
]]></description>
<dc:creator><![CDATA[Wu, K, Politis, M, Piccini, P]]></dc:creator>
<dc:date>Thu, 05 Nov 2009 10:01:51 PST</dc:date>
<dc:identifier>info:doi/10.1136/pgmj.2008.075820</dc:identifier>
<dc:title><![CDATA[Parkinson disease and impulse control disorders: a review of clinical features, pathophysiology and management]]></dc:title>
<dc:publisher>The Fellowship of Postgraduate Medicine</dc:publisher>
<prism:number>1009</prism:number>
<prism:volume>85</prism:volume>
<prism:endingPage>596</prism:endingPage>
<prism:publicationDate>2009-11-01</prism:publicationDate>
<prism:startingPage>590</prism:startingPage>
<prism:section>Reviews</prism:section>
</item>

<item rdf:about="http://pmj.bmj.com/cgi/content/short/85/1009/597?rss=1">
<title><![CDATA[Multimodality imaging in hyperparathyroidism]]></title>
<link>http://pmj.bmj.com/cgi/content/short/85/1009/597?rss=1</link>
<description><![CDATA[
<p>Imaging of patients with hyperparathyroidism has evolved over the last decade and transformed surgical management of the disease. Traditional bilateral neck dissection and exploratory surgery has been overtaken by focused, minimally invasive procedures in patients with single-gland disease. Accurate preoperative localisation of the involved parathyroid gland is the cornerstone for success of the new surgical techniques. In this article, the strengths, limitations and respective roles of different imaging modalities used to evaluate patients with hyperparathyroidism will be reviewed.</p>
]]></description>
<dc:creator><![CDATA[Patel, C N, Scarsbrook, A F]]></dc:creator>
<dc:date>Thu, 05 Nov 2009 10:01:51 PST</dc:date>
<dc:identifier>info:doi/10.1136/pgmj.2008.077842</dc:identifier>
<dc:title><![CDATA[Multimodality imaging in hyperparathyroidism]]></dc:title>
<dc:publisher>The Fellowship of Postgraduate Medicine</dc:publisher>
<prism:number>1009</prism:number>
<prism:volume>85</prism:volume>
<prism:endingPage>605</prism:endingPage>
<prism:publicationDate>2009-11-01</prism:publicationDate>
<prism:startingPage>597</prism:startingPage>
<prism:section>Reviews</prism:section>
</item>

<item rdf:about="http://pmj.bmj.com/cgi/content/short/85/1009/606?rss=1">
<title><![CDATA[Hybrid SPECT/CT: the end of "unclear" medicine]]></title>
<link>http://pmj.bmj.com/cgi/content/short/85/1009/606?rss=1</link>
<description><![CDATA[
<p>The emergence of hybrid imaging, combining anatomical computed tomography (CT) and functional scintigraphic imaging has increased the armoury of techniques available to image disease. Single photon emission computed tomography/CT (SPECT/CT) is a dual modality technique which increases the sensitivity and specificity of existing radionuclide imaging and helps characterise equivocal lesions detected by other imaging methods. In addition to the many established clinical applications for SPECT/CT, there are new clinical uses emerging in a spectrum of benign and malignant diseases. In this article, we will discuss the established and emerging uses of hybrid SPECT/CT and illustrate the incremental value of the technique in a variety of clinical applications.</p>
]]></description>
<dc:creator><![CDATA[Patel, C N, Chowdhury, F U, Scarsbrook, A F]]></dc:creator>
<dc:date>Thu, 05 Nov 2009 10:01:51 PST</dc:date>
<dc:identifier>info:doi/10.1136/pgmj.2008.077859</dc:identifier>
<dc:title><![CDATA[Hybrid SPECT/CT: the end of "unclear" medicine]]></dc:title>
<dc:publisher>The Fellowship of Postgraduate Medicine</dc:publisher>
<prism:number>1009</prism:number>
<prism:volume>85</prism:volume>
<prism:endingPage>613</prism:endingPage>
<prism:publicationDate>2009-11-01</prism:publicationDate>
<prism:startingPage>606</prism:startingPage>
<prism:section>Reviews</prism:section>
</item>

<item rdf:about="http://pmj.bmj.com/cgi/content/short/85/1009/614?rss=1">
<title><![CDATA[The metabolic syndrome: common origins of a multifactorial disorder]]></title>
<link>http://pmj.bmj.com/cgi/content/short/85/1009/614?rss=1</link>
<description><![CDATA[
<p>The metabolic syndrome (MetS) represents a combination of cardiometabolic risk determinants including obesity (central adiposity), insulin resistance, glucose intolerance, dyslipidaemia, non-alcoholic fatty liver disease and hypertension. MetS is rapidly increasing in prevalence worldwide as a consequence of the continued obesity "epidemic", and as a result will have a considerable impact on the global incidence of cardiovascular disease and type 2 diabetes. Currently, there is debate concerning whether the risk of cardiovascular disease is greater in patients diagnosed with MetS than that of the sum of the individual risk factors. At present, no unifying origin that can explain the pathogenesis of MetS has been identified and therefore no unique pharmacological treatment is available. This review summarises and critically evaluates the current clinical and scientific evidence supporting the existence of MetS as a multifactorial endocrine disease, for which maternal nutrition may be a common pathogenic mechanism. In addition, we suggest that ectopic fat accumulation (such as visceral and hepatic fat accumulation) and the proinflammatory state are central to the development of the MetS.</p>
]]></description>
<dc:creator><![CDATA[Bruce, K D, Byrne, C D]]></dc:creator>
<dc:date>Thu, 05 Nov 2009 10:01:51 PST</dc:date>
<dc:identifier>info:doi/10.1136/pgmj.2008.078014</dc:identifier>
<dc:title><![CDATA[The metabolic syndrome: common origins of a multifactorial disorder]]></dc:title>
<dc:publisher>The Fellowship of Postgraduate Medicine</dc:publisher>
<prism:number>1009</prism:number>
<prism:volume>85</prism:volume>
<prism:endingPage>621</prism:endingPage>
<prism:publicationDate>2009-11-01</prism:publicationDate>
<prism:startingPage>614</prism:startingPage>
<prism:section>Reviews</prism:section>
</item>

<item rdf:about="http://pmj.bmj.com/cgi/content/short/85/1009/622?rss=1">
<title><![CDATA[Diagnosis and new treatments in muscular dystrophies]]></title>
<link>http://pmj.bmj.com/cgi/content/short/85/1009/622?rss=1</link>
<description><![CDATA[
<p>Duchenne muscular dystrophy (DMD), Becker muscular dystrophy (BMD) and limb girdle muscular dystrophies (LGMD) represent a significant proportion of paediatric and adult neuromuscular neurology practice. The proactive symptom-based multidisciplinary team (MDT) management and access to non-invasive ventilation have enabled improved survival into adulthood. Nevertheless the severe disability imposed by conditions such as DMD poses a challenge for successful transition of care and management for paediatric and adult neurology teams. DMD is discussed in detail as a paradigm illustrating diagnosis, management and role for different pharmacological interventions to improve survival, but also challenges in adulthood care, and cutting-edge therapies. LGMDs are much rarer than DMD and BMD, and in addition there is a significant genetic and clinical heterogeneity, which leads to diagnostic difficulties. The clinical and laboratory diagnostic features of seven LGMD subtypes are summarised, and their allelic "non-limb girdle" phenotypes are tabulated to illustrate the theme of one gene causing multiple clinical phenotypes, with the aim of refining the clinician&rsquo;s diagnostic approach. The lessons learnt from DMD MDT management to improve survival are broadly applicable to LGMDs with severe motor disability/multisystem complications.</p>
]]></description>
<dc:creator><![CDATA[Manzur, A Y, Muntoni, F]]></dc:creator>
<dc:date>Thu, 05 Nov 2009 10:01:51 PST</dc:date>
<dc:identifier>info:doi/10.1136/jnnp.2008.158329</dc:identifier>
<dc:title><![CDATA[Diagnosis and new treatments in muscular dystrophies]]></dc:title>
<dc:publisher>The Fellowship of Postgraduate Medicine</dc:publisher>
<prism:number>1009</prism:number>
<prism:volume>85</prism:volume>
<prism:endingPage>630</prism:endingPage>
<prism:publicationDate>2009-11-01</prism:publicationDate>
<prism:startingPage>622</prism:startingPage>
<prism:section>Reviews</prism:section>
</item>

<item rdf:about="http://pmj.bmj.com/cgi/content/short/85/1009/631?rss=1">
<title><![CDATA[A beginner's guide to sex]]></title>
<link>http://pmj.bmj.com/cgi/content/short/85/1009/631?rss=1</link>
<description><![CDATA[]]></description>
<dc:creator><![CDATA[Launer, J.]]></dc:creator>
<dc:date>Thu, 05 Nov 2009 10:01:51 PST</dc:date>
<dc:identifier>info:doi/10.1136/pgmj.2009.090639</dc:identifier>
<dc:title><![CDATA[A beginner's guide to sex]]></dc:title>
<dc:publisher>The Fellowship of Postgraduate Medicine</dc:publisher>
<prism:number>1009</prism:number>
<prism:volume>85</prism:volume>
<prism:endingPage>632</prism:endingPage>
<prism:publicationDate>2009-11-01</prism:publicationDate>
<prism:startingPage>631</prism:startingPage>
<prism:section>On reflection</prism:section>
</item>

</rdf:RDF>