Table 1

Pathological features of acute demyelinating disorders (modified from Scully et al23)

FeatureADEMAcute multiple sclerosisAcute haemorrhagic leucoencephalitisNeuromyelitis optica
Perivascular infiltrates
    Lymphocytes++++++++
    Macrophages or monocytes++++++++
    Polymorphs++++
    Eosinophils++
Perivascular haemorrhage++
Necrotising venules+++
Perivascular demyelination±±++++
Axonal damage±±++++