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Darier disease: candy-cane nails and hyperkeratotic papules
  1. Pierre Halteh,
  2. Joseph L Jorizzo,
  3. Shari R Lipner
  1. Department of Dermatology, Weill Cornell Medicine, New York, New York, USA
  1. Correspondence to Dr Shari Lipner, Department of Dermatology, Joan and Sanford I Weill Medical College of Cornell University, 1305 York Avenue, New York, NY 10021, USA; SHL9032{at}med.cornell.edu

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Case

A 43-year-old woman presented to our clinic with nail changes and a pruritic malodourous rash on the neck and trunk that began 27 years earlier. Her mother had similar cutaneous and nail findings. Physical examination of her fingernails revealed alternating red and white longitudinal bands, with V-shaped notches at the distal nail edges (figure 1). Clinical evaluation of the skin showed numerous hyperkeratotic papules and plaques on her neck, chest, submammary region and abdomen (figure 2). After treatment with compounded triamcinolone, Silvadene ointment and oral glycopyrrolate, her rash and symptoms were ameliorated. Genetic …

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