Article Text

PDF
Depiction of myocardial crypts in hypertrophic cardiomyopathy by cardiovascular MRI
  1. Edward T D Hoey1,
  2. Jun K Teoh2,
  3. Vijayabhaskar Pakala1,
  4. Arul Ganeshan1
  1. 1Department of Radiology, Heart of England NHS Trust, Heartlands hospital, Birmingham, West Midlands, UK
  2. 2Department of Cardiology, Heart of England NHS Trust, Heartlands hospital, Bordesley Green East, Birmingham, West Midlands, UK
  1. Corrrespondence to
    Dr Edward T D Hoey, Department of Radiology, Heart of England NHS Trust, Heartlands hospital, Bordesley Green East, Birmingham, West Midlands B9 5SS, UK; edwardhoey1{at}gmail.com

Statistics from Altmetric.com

Introduction

Myocardial crypts are increasingly recognised as a novel MRI marker of genotype-positive hypertrophic cardiomyopathy (HCM) and have been the subject of several recent landmark imaging papers. Maron et al1 have shown that 61% of genotype-positive/phenotype-negative HCM patients (cohort derived from screening family members of known HCM) have myocardial crypts. Conversely, the prevalence of myocardial crypts is low (4%) in patients who are both genotype and phenotype positive for HCM. The emerging use of myocardial crypt identification on MRI may therefore be to identify family members of HCM patients who are likely to be asymptomatic HCM mutation carriers.1–3

Case and imaging

A 20-year-old man having normal blood pressure was found to have asymmetric …

View Full Text

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.