Pulmonary alveolar proteinosis treatment by whole-lung lavage
- Division of Pulmonary Medicine, First Affiliated Hospital of Wenzhou Medical College, Wenzhou, China
- Correspondence to Yuping Li, Division of Pulmonary Medicine, First Affiliated Hospital of Wenzhou Medical College, Fuxue Lane No. 2, Wenzhou 32500, China; wzres686{at}163.com
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Contributors CC has contributed to conception and design, and carried out the manuscript preparation. MY and HX have carried out acquisition and interpretation of data. YL has revised it critically for important intellectual content and provided final approval of the version to be published. All authors have read and approved the final manuscript. All authors participated in determining the order of authorship.
Pulmonary alveolar proteinosis (PAP) is a rare condition which is characterised by the abnormal accumulation of proteinaceous material in the alveolar spaces, with resulting impairment in oxygen exchange across the involved alveoli. The diagnosis of PAP can be established by the classic ‘milky’ effluent bronchoalveolar lavage fluid (BALF). The current effective treatment for PAP is whole-lung lavage (WLL). We offer one case of PAP with apparent presentations and the clinical course. This report provides some information about the diagnosis and treatment of PAP (see PAP video online).
A 39-year-old man, an ex-smoker, was brought to our respiratory department due to dry cough and progressive exertional dyspnoea for 7 months. He had …








