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Postgrad Med J 84:385 doi:10.1136/jnnp.2007.127563
  • Cochrane corner

Multidisciplinary rehabilitation for adults with multiple sclerosis

  1. F Khan1,
  2. L Turner-Stokes2,
  3. L Ng3,
  4. T Kilpatrick4
  1. 1
    Department of Rehabilitation Medicine, University of Melbourne, Royal Melbourne Hospital, Melbourne, Australia
  2. 2
    Herbert Dunhill Chair of Rehabilitation, Kings College London, UK and Regional Hospital Unit, Northwick Park Hospital, Harrow, Middlesex, UK
  3. 3
    Neurorehabilitation Unit, Royal Melbourne Hospital, Melbourne, Australia
  4. 4
    Centre for Neuroscience, The University of Melbourne, Melbourne, Australia
  1. Dr F Khan, Department of Rehabilitation Medicine, University of Melbourne, Royal Melbourne Hospital, Parkville VIC 3052, Australia; fary.khan{at}mh.org.au
  • Received 24 June 2007
  • Revised 11 September 2007
  • Accepted 19 September 2007

Multidisciplinary rehabilitation (MDR) is an important component of symptomatic and supportive treatment for multiple sclerosis (MS), but evidence base for its effectiveness is yet to be established.

OBJECTIVE

To assess the effectiveness of organised MDR in adults with MS. MDR was defined as an inpatient, outpatient, home or community based programme, delivered by two or more disciplines in conjunction with physician consultation, and targeted towards improvements at the level of activity and/or participation.

METHODS

The Cochrane MS Group methods search strategy identified all randomised (RCT) and controlled (CCT) clinical trials that compared MDR with routinely available local services or lower levels of intervention, or trials comparing interventions in different settings or at different levels of intensity. Three reviewers selected trials and rated their methodological quality …