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Postgrad Med J 2007;83:731-737 doi:10.1136/pgmj.2007.061994
  • Review

Gene therapy in head and neck cancer: a review

  1. E Chisholm*,1,
  2. U Bapat*,1,
  3. C Chisholm3,
  4. G Alusi2,
  5. G Vassaux1
  1. 1
    Molecular Oncology, Cancer Research UK, Barts and The London NHS Trust, London, UK
  2. 2
    Department ENT, Barts and The London NHS Trust, London, UK
  3. 3
    Department of Clinical Oncology, Charing Cross Hospital, Hammersmith, London, UK
  1. Dr E Chisholm, 44 Eastbury Grove, London W4 2JY, UK; edwardchisholm{at}doctors.org.uk
  • Received 26 May 2007
  • Accepted 9 October 2007

Abstract

Gene therapy for cancer is a rapidly evolving field with head and neck squamous cell cancer being one of the more frequently targeted cancer types. The number of clinical trials in the UK is growing and there is already a commercially available agent in China. Various gene therapy strategies along with delivery mechanisms for targeting head and neck cancer are reviewed.

Footnotes

  • Competing interests: None declared

  • ↵*Also Department ENT, Barts and The London NHS Trust, London, UK

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