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One-year-old male with accelerated growth and development
  1. Ajit Singh Kashyap1,
  2. Kuldip Parkash Anand2,
  3. Surekha Kashyap3,
  4. Sumeet Arora4
  1. 1
    Department of Endocrinology, Command Hospital (Central Command), Lucknow Cantt, India
  2. 2
    Command Hospital (Eastern Command), Kolkata, India
  3. 3
    Command Headquarters (Central Command), Medical Branch, Lucknow, India
  4. 4
    Department of Radiology, Command Hospital (Central Command), Lucknow, India
  1. Dr Ajit Singh Kashyap, Department of Endocrinology, Command Hospital (Central Command), Lucknow Cantt 226 002, India; kashyapajits{at}


A 1-year-old male child with isosexual central (gonadotropin-dependent) precocious puberty caused by hypothalamic hamartoma is reported. Details of the diagnosis based solely on neuromaging characteristics, and satisfactory results of medical treatment with gonadotropin releasing hormone agonist analogues, are highlighted.

  • hypothalamic hamartoma
  • precocious puberty

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  • Competing interests: nil

  • Source of funding: nil

  • Abbreviations:
    central nervous system
    fluid attenuated inversion recovery
    gonadotropin dependent precocious puberty
    gonadotropin releasing hormone
    luteinising hormone
    luteinising hormone releasing hormone
    magnetic resonance imaging

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