Article Text

PDF
Classical diseases revisited: transient global amnesia
  1. D Owen,
  2. B Paranandi,
  3. R Sivakumar,
  4. M Seevaratnam
  1. Department of Medicine, Queen Elizabeth II Hospital, Welwyn Garden City, Hertfordshire, UK
  1. Correspondence to:
 Dr R Sivakumar
 89 Goring Road, Ipswich IP4 5LP, UK; sivasiva51{at}hotmail.com

Abstract

Transient global amnesia usually affects patients between the ages of 40 and 80. Patients with this condition are often described – wrongly – as being confused. It presents classically with an abrupt onset of severe anterograde amnesia. It is usually accompanied by repetitive questioning. The patient does not have any focal neurological symptoms. Patients remain alert, attentive, and cognition is not impaired. However, they are disoriented to time and place. Attacks usually last for 1–8 h but should be less than 24 h. It is possible that it may result from different mechanisms such as venous congestion with valsalva-like activities before symptom onset, arterial thromboembolic ischaemia and vasoconstriction due to hyperventilation. Diagnosis may be made safely in the presence of a characteristic collateral history. No specific treatment is indicated for a typical episode.

  • ACS, acute confusional state
  • CPS, complex partial seizures
  • DWI, diffusion-weighted imaging
  • TEA, transient epileptic amnesia
  • TGA, transient global amnesia
  • TIA, transient ischaemic attack
  • transient global amnesia
  • memory disturbance

Statistics from Altmetric.com

Footnotes

    Request permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.