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Postgrad Med J 2007;83:87-94 doi:10.1136/pgmj.2006.046078
  • Review

Cryoglobulinaemic vasculitis: classification and clinical and therapeutic aspects

  1. Gerald S Braun1,
  2. Sophia Horster3,
  3. Katrin S Wagner4,
  4. Stephan Ihrler5,
  5. Holger Schmid2
  1. 1Division of Nephrology and Immunology, RWTH University, Aachen, Germany
  2. 2Medical Policlinic, Ludwig-Maximilians-University, Munich, Germany
  3. 3Department of Dermatology, Ludwig-Maximilians-University, Munich, Germany
  4. 4Renal Unit, Department of Medicine II, Klinikum Rechts der Isar, Technical University, Munich, Germany
  5. 5Department of Pathology, Ludwig-Maximilians-University, Munich, Germany
  1. Correspondence to:
 Dr Holger Schmid
 Medizinische Poliklinik, Ludwig-Maximilians-Universität München, Pettenkoferstr 8a, 80336 Munich, Germany; holger.schmid{at}lrz.uni-muenchen.de
  • Received 1 February 2006
  • Accepted 11 August 2006

Abstract

Cryoglobulinaemia may cause cutaneous vasculitis and glomerulonephritis, potentially leading to end stage renal failure. An important proportion of cryoglobulinaemias are secondary to hepatitis C virus infection. Emerging antiviral treatment options offer a chance for causal therapy of these cases of cryoglobulinaemia. This review summarises the classification and clinical and therapeutic aspects of cryoglobulinaemic vasculitis and glomerulonephritis.

Footnotes

  • Funding: None.

  • Competing interests: None.

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